Links & Glossary
Nuclear Med. Glossary E-H
The Nuclear Medicine Glossary by Richard Zimmerman, IBA Letters E to H
the equivalent dose corrected by the weighting coefficient relating to the irradiated tissue (0.05 for the thyroid, 1 for the whole body) expressed in sieverts.
radioactive half-life corrected by the biological half-life. With this information, the practitioner can estimate how long a radioactive substance that has been ingested by or injected into a patient will take before generating an effect on the organism (or a certain type of cell or tissue).
European Medicines Evaluation Agency, European Health Authority: decentralised agency of the European Union, located in London. Recently renamed as EMA: European Medicines Agency
Equivalent dose or Dose equivalent:
absorbed dose corrected by a weighting coefficient relating to the radiation (1 for X-rays, β-rays, and γ-rays, 20 for α-rays), expressed in sieverts. This is a value used in radiation protection to take account of the difference in biological effect of the various types of radiation.
method of therapy by irradiation using a source external to the patient (former cobalt therapy, but now X-ray therapeutic beams and also neutron therapy or proton therapy). Domain of the radiotherapist.
Food and Drug Administration, American Health Authority.
substance labeled with fluorine-18, most frequently used for diagnosis based on positron emission tomography technology. A radiolabeled glucose analog that allows glucose-consuming cells such as tumor cells to be displayed.
an extremely reactive chemical entity which contains a redundant electron and which is at the origin of later chemical transformations.
study of the method of administering a medication.
radiation of a shorter wavelength than X-rays emitted by certain radionuclides and with very high energy; usable for diagnostic imaging.
tool for the production of a radioisotope by the decay of a parent radionuclide from which it is regularly separated by a physical means (column filtration, extraction).
Good Manufacturing Practice, the present highest industry standards for drug production. GLP stands for Good Laboratory Practice (Research) and GCP for Good Clinical Practice (Clinical Research and Development).
unit of absorbed dose corresponding to one joule per kilogram. The former unit of absorbed dose is the rad, with one gray equaling 100 rads.
radioactive half-life, see Radioactive half-life. The term biological half-life is also used, which corresponds to the time at the end of which half the quantity of a substance has disappeared or been eliminated from a cell by a biological process.